MyBioSource.com's TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15) Antibody was generated using ELOC, elongin C, and TCEB1 as the antigen and it reacts with Human.
Description
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation